Harnessing CD8 ⁺ T?cell exhaustion to treat type 1 diabetes

Complementary and Alternative Medicine to Treat Diabetes Mellitus Type 1 in Southern Iran

complementary and alternative medicine to treat diabetes mellitus type 1 in southern iran

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Tcell subset described as CD 4 loCD 40 + Tcells ( TCD 40 ) in human type 1 diabetes

a The Webb-Waring Institute, University of Colorado at Denver and Health Sciences Center, 4200 East 9th Ave, Denver, CO, USA b The Barbara Davis Childhood Diabetes Center, University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA c UCSF Diabetes Center, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA, USA d TheDepartmentofMedicine,University of C...

Harnessing the immune system to treat cancer.

A major challenge for the immune system is to recognize and eliminate cells undergoing carcinogenesis. Immune defense against tumors is complex. It can be mediated early by the innate immune system (i.e., phagocytes, NK cells, NKT cells, cytokines, and complement proteins) and later by the adaptive immune system (i.e., B cells and T cells). The eight articles in this Review series on tumor immu...

Harnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes.

Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing β-cells in the pancreatic islets. There is an immediate need to restore both β-cell function and immune tolerance to control disease progression and ultimately cure T1D. Currently, there is no effective treatment strategy to restore glucose regulation in patients with T1D. FoxP3-expressing CD4(+) regulatory T cells (...